Avoid High Carb Evening Meals With Prediabetes: New Study

Scientists know our metabolism, and the body’s processing of glucose is influenced by our circadian rhythms, or internal clock. To learn more about the interaction between diet and our internal clock’s regulation of glucose metabolism, some German scientists conducted a nutrition study involving 29 men.

The study subjects were normal to overweight, with an average age of 46. Eleven of them had high fasting blood sugar levels, or other signs of pre-diabetes. The other 18 subjects had normal glucose measurements.

Each participant followed two different diets for four weeks each. Both diets, A and B, contained an equal amount of calories, fats, carbohydrates, and proteins. The two plans differed in what time of day the subjects ate mostly fats, or mostly carbohydrates.

While on plan A, subjects consumed a carbohydrate-rich diet from early morning until 1:30 p.m., and then ate high-fat foods from 4:30 p.m. to 10:00 p.m. When on plan B, high-fat food was eaten until early afternoon, and carbohydrate-rich fare was consumed in the afternoon and evening.

The researchers found that in men with pre-diabetes, the consumption of carbohydrate-rich foods in the evening had a negative effect on blood glucose regulation. Their glucose levels were 7.9 percent higher than when high-fat foods were eaten later in the day. In participants with healthy glucose metabolism, the timing of carbohydrate intake did not make a significant difference in glucose levels.

It was also found that subjects with pre-diabetes had altered secretions of two intestinal hormones that help regulate glucose metabolism, and these secretions are influenced by a particular circadian rhythm. “The circadian rhythm of the hormonal release thus influences the way we react to carbohydrates,” said endocrinologist and researcher Andreas Pfeiffer, German Institute of Human Nutrition.

Because of their findings, the researchers recommend people with pre-diabetes align themselves to their internal clock and avoid carbohydrate-rich meals in the late afternoon, and evening.

Source: Science Daily

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