Duke University Research Leads to Long-term Type 2 Insulin Injection

A new biopolmer injection could replace daily or weekly insulin shots with a bi-weekly or monthly injection. The new development was created by researchers at Duke University in North Carolina and published as a paper in Nature.

The injection method could improve the lives of millions of diabetics who struggle with dosages and variances in their diets and insulin intake.

Insulin demands in the body are always changing, making dosing difficult.

Newer drugs use glucagon-like peptide-1 (GLP1) receptor angonists. These use a signaling molecule (GLP1) to trigger insulin release in the pancreas. Unfortunately, GLP1 has a short life in the body, so direct injections only provide fleeting help. Several experiments to fuse GLP1 with different compounds in order to extend its usefulness in the body have created drugs capable of regulating insulin for up to a week.

Now, Duke researchers think they can extend that to two weeks or even a month. By using biopolymer (bio-plastic) that encases the GLP1 and releases it based on body heat reactions. The biopolymer forms a gel that slowly releases the GLP1 into the blood stream at a steady rate over time. Without the usual "peaks and troughs" of GLP1 injections in other forms.

In some cases, the biopolymer-encased GLP1 could last three times as long as in other common methods. The Duke University teams is continuing with animal studies and working towards human trials. They also plan to expand the biopolymer's use into other drugs, such as pain medications.

Source: MedicalNewsToday.com

Get A Free 7 Day Diabetes Meal Plan

Get a free 7-Day Diabetes Meal Plan from Constance Brown-Riggs who is a Registered Dietitian-Certified Diabetes Educator and who is also a national spokesperson for the American Dietetic Association.

Just enter in your email below to download your free Diabetes Meal Plan.

By clicking Submit, you agree to send your info to InformationAboutDiabetes.com who may contact you with updates and information and we agree to use it according to our privacy policy.

More Articles

Chamomile tea has long been prized for its calming properties, but few people realize it’s also beneficial for glucose regulation. Traditionally,...

Matcha tea is a rich, creamy, full-bodied beverage with amazing nutritional properties that address several diabetes health concerns. The trace...

One way to ensure our body gets a variety of nutrients is eating nutrient-dense foods, and one of the most nutrient-dense foods on our planet is...

It would be interesting to know how many people with diabetes actually use blood glucose control solutions to regularly check the accuracy of...

A mood is an internal state or condition of feeling. It colors everything else we experience, much like colored sunglasses add a tint to...

More Articles

Chamomile tea has long been prized for its calming properties, but few people realize it’s also beneficial for glucose regulation. Traditionally,...

Hot weather does not directly alter blood glucose levels. However, sweltering temperatures affect our metabolism and the release of hormones. Heat...

Those who have not yet been diagnosed with type 2 diabetes can greatly reduce their susceptibility by doing one key...

With such a marked increase in the number of new diabetes cases, more people are wondering if type 1 diabetes...

Although diabetes is common, many people who have been diagnosed do not completely understand how it develops or whether it is hereditary....

Any sweetener you use to replace table sugar is a sugar substitute. One type of sugar substitute is artificial sweetener. Three other types...

It would be interesting to know how many people with diabetes actually use blood glucose control solutions to regularly check the accuracy of...

One way to ensure our body gets a variety of nutrients is eating nutrient-dense foods, and one of the most nutrient-dense foods on our planet is...

Diabetes is a health condition that disrupts the body’s normal production of insulin. Currently, more than one million Americans are diagnosed...

The HbA1c blood test, more commonly known as the A1C, is both a very useful and a very cool calculation of your average blood glucose levels over...

The different sugar content of fruits can be confusing when you are trying to manage your...

A diabetes meal plan is a guide indicating what types of foods, and how much of them, people should eat at meal and snack time. Following a meal...

Because it is Peripheral Neuropathy Awareness Week (May 7-13), this article is about a device people with neuropathy may not be aware of—a device...

=It’s helpful to know the difference between a food’s total grams of carbohydrate, and net grams of carbohydrate since only net carbs affect blood...

Everyone from grandmothers to physicians tout oatmeal's wholesome goodness and health benefits. But, is oatmeal good for diabetics? Limited...