New clues as to why weight-loss surgery cures diabetes

Many patients who undergo gastric bypass surgery also experience a remission in diabetes, according to researchers at Manchester University.

But other than attributing this result to weight loss, scientists haven't exactly known why surgical weight-loss procedures can cure the blood sugar condition – until now.

UK researchers found that gut hormone cells, previously thought to contain just one hormone, have up to six hormones, including the "hunger" hormone, ghrelin.

Under normal circumstances, these cells "taste" what we eat and respond by releasing hormones that trigger the pancreas to control insulin levels.

Yet these cells can malfunction as a result of overeating or undereating, said study leader Dr. Craig Smith, senior lecturer in molecular cell physiology.

Cell changes could hold diabetes cure

According to Smith, the most common type of gastric bypass surgery also bypasses a proportion of gut hormone cells. As a result, these cells can become altered and reprogrammed.


"For us, understanding how these cells change in response to surgery is likely to hold the key to a cure for diabetes," Smith said.

In people who are obese and also have diabetes, 75 percent of them are cured of diabetes after gastric bypass, he noted.

"Understanding the messages the gut sends out when we eat food and when things go wrong, as is the case in diabetes, is our next challenge and hopefully one that will result in the development of drugs which could be used instead of surgery to cure obesity and prevent diabetes."

A recent report from the UK's National Institute of Health and Care Excellence suggested that obese people suffering from type 2 diabetes should be automatically considered for bariatric surgery. Current rules in the country hold that only patients who are morbidly obese are offered the procedure.


The study is published in the journal Endocrinology.

Source: Manchester University

Image credit: vorakorn/FreeDigitalPhotos.net


More Articles

Having diabetes is cause for concern, however it doesn’t mean that you need to eliminate all of your favorite foods from your diet completely....

With diabetes becoming more of an epidemic each and every day, being knowledgeable about the disease, its effects on the body as well as ways to...

If you’re a diabetic or live with one, it can be tough trying to figure out the best foods to eat because your priority is to control your blood...

In this post, I will show you the 10 best ice creams for diabetics.

When you think of sweetened foods that a diabetic shouldn’t consume,...

If you’re living with diabetes, snacking is a necessity because going for more than 3-4 hours without eating can be detrimental to your health....

More Articles

For diabetics, choosing healthy snacks can be a daunting task.

A good rule of thumb is to pick out snacks that are rich in protein, fiber,...

According to information available through the National Institutes of Health, there’s an estimated 462 million people in the world who are...

Eleven Clinical Studies

After eleven clinical studies and 300,000 participants, researcher Vasanti Malik and her team of researchers...

Diabetic women often have a harder time losing weight than non-diabetic women. A study funded by Jenny Craig proved that diabetic women have an...

Many recent studies have proved that magnesium levels are lower in patients with diabetes than in non-diabetics. This magnesium...

Fluid retention, also known as edema, is a problem that affects many diabetics, especially those with type 2 diabetes...

Some of us might be thrilled if we could manage our blood sugar by sitting in a hot tub or sauna, instead of working up a sweat biking, or using...

Cooking and baking with the ancient cereal grain sorghum has health benefits for people with diabetes, and those with weight control issues....

When it comes to certain foods, there are always questions as to whether or not a diabetic can have them without...

With its slightly nutty flavor, chewy texture, and nutritional punch farro is an ancient whole grain worth a place in our pantry.

Farro...

Matcha tea is a rich, creamy, full-bodied beverage with amazing nutritional properties that address several diabetes health concerns.

The...

Salads are good example of foods that type 2 diabetics can enjoy with relatively low guilt. With the right greens and other elements added, salad...

Remaining gainfully employed is important to many people. Those who live with any form of diabetes may find that some lines of work are more...

Learning that you have diabetes does mean making some lifestyle changes. One of the areas that needs attention is your diet. Most people find that...

One of the more challenging aspects of life as a type 2 diabetic is managing your diet. There’s often the temptation to avoid certain foods...