Exercise in a Bottle? New Drugs May Mimic Physical Activity

The benefits of exercise might soon be available in pill form, according to new research from the University of Sydney.

A team from the school's Charles Perkins Centre found more than 1,000 molecular changes that occur in muscles when we exercise, providing researchers with the first-of-its-kind "blueprint" for exactly what happens when the body gets physical activity.

“Exercise is the most powerful therapy for many human diseases, including type 2 diabetes, cardiovascular disease and neurological disorders,” said Professor David James, head of the research team that led the study.

However, according to James, exercise isn't always a treatment option for some patients, which means developing drugs that mimic its effects could be groundbreaking.

A 'major breakthrough'

In the study, researchers analyzed the human skeletal muscle biopsies of four healthy males after 10 minutes of high-intensity exercise. A technique called protein phosphorylation was used to analyze the changes that occurred in the muscles after physical activity.

“Exercise produces an extremely complex, cascading set of responses within human muscle. It plays an essential role in controlling energy metabolism and insulin sensitivity,” said co-author Dr Nolan Hoffman.

A pill can't completely replace exercise, Hoffamn warned, but the goal is to replicate the most critical of the 1,000+ changes the researchers observed into some type of treatment that could help stave off serious health conditions like heart disease or insulin resistance.

“While scientists have long suspected that exercise causes a complicated series of changes to human muscle, this is the first time we have been able to map exactly what happens," he said.

Source: University of Sydney

Get a Free Diabetes Meal Plan

Get a free 7-Day Diabetes Meal Plan from Constance Brown-Riggs who is a Registered Dietitian-Certified Diabetes Educator and who is also a national spokesperson for the American Dietetic Association.

Just enter in your email below to download your free Diabetes Meal Plan.

By clicking Submit, you agree to send your info to InformationAboutDiabetes.com who may contact you with updates and information and we agree to use it according to our privacy policy.

More Articles

Limiting our intake of highly processed foods, and eating more whole and lightly processed fare can boost our nutrient and fiber intake, lower...

Chamomile tea has long been prized for its calming properties, but few people realize it’s also beneficial for glucose regulation. Traditionally,...

Today, the healing benefits of essential oils are more than the claims of ancient tradition and alternative medicine. They are increasingly the...

The different sugar content of fruits can be confusing when you are trying to manage your...

There is nothing close to a one-size-fits-all exercise program for those with diabetic peripheral neuropathy. The best general advice is to...

More Articles

Stomach aches and other gastrointestinal pains can be signs of a bigger problem. One such problem for diabetics is gastroparesis, or delayed...

Two of the most common symptoms of diabetes are increased thirst and increased urine production. These symptoms are so prevalent in diabetics that...

The different sugar content of fruits can be confusing when you are trying to manage your...

Chamomile tea has long been prized for its calming properties, but few people realize it’s also beneficial for glucose regulation. Traditionally,...

There is nothing close to a one-size-fits-all exercise program for those with diabetic peripheral neuropathy. The best general advice is to...

If your child has diabetes, you want him or her to be safe while in school and to have the same educational opportunities as other children....

Do not let pictures of yoga experts with their bodies twisted into bizarre, compact shapes fool you. Even people with stiff muscles, creaky joints...

The American Diabetes Association estimates that more than 7 million people in the United States have diabetes but don’t know it yet. These people...

While some celebrities aren't quick to talk about living with diabetes, others are quite transparent and inspiring - acting as advocates for the...

People with diabetes are about twice as likely to experience heart disease as those without the condition, making cardiovascular health a critical...

Pilates is an exercise method proven to improve flexibility, strength, coordination, muscular stamina, balance, and posture. Many Pilates...

All diabetics know that maintaining proper blood sugar levels is the lifeline...

It can be difficult enough to get on stage and make a roomful of strangers laugh, but for comedians suffering from type 1 or type 2 diabetes,...

Most people with insulin-dependent diabetes use syringes and lancets every day. However, many of them do not know how to dispose of these...

Explaining diabetes to children can seem like a daunting task, but in reality, it is no more difficult than discussing anything else important....