How Can I Tell If Diabetes Research Is Valid?

New findings from medical research on diabetes are published nearly every week. Keeping up with the latest studies can help us maintain optimal health—if we read them with a critical eye.

Clinical Trials

Much of the research we come across involves clinical trials that test whether an intervention might be helpful and safe for patients to use:

  • Some clinical trials are pilot studies that explore the potential efficacy and safety of a new drug or treatment.
  • Other research involves well-planned, complicated, and lengthy clinical trials that measure an intervention’s effectiveness, and determine possible side effects.

Pilot studies are typically small, but positive results often lead to the larger, more complex clinical trials.

Questions To Ask

Whether reading about a pilot study, or an in-depth clinical trial, there are several questions we should be asking to assess the study’s validity. Seeking answers to these questions helps us become informed and discriminating healthcare consumers:

  • How big was the study? The accuracy of a study is generally increased when many people participate. In smaller studies, there is a greater probability that observed effects are owed to chance.
  • Was the clinical trial controlled? In typical controlled clinical trials, experimental treatments are compared to standard treatments with known effects, or to placebos. For instance, one group of participants will receive an experimental retinopathy treatment, and their outcomes are compared to the outcomes of a control group receiving either the standard retinopathy treatment, or a sham treatment (placebo).
  • Was bias minimized? It’s difficult to avoid bias when running clinical trials, especially if patients, and (or) the investigators know which treatment - experimental, standard, or placebo - each participant is receiving.
  • Ideally, study participants are randomly assigned to either the experimental or the control group, and are “blind” or unaware which group they are in. In rigorous double-blind studies, neither the participants, nor the researchers know which volunteers are getting the experimental intervention.
  • Conflicts of interest? A study’s credibility is suspect when the investigators or research sponsors have a monetary or reputational “stake” in certain outcomes. Be attentive to who funds a study, whom the investigators work for, and look for corroborating research evidence from independent scientific sources.
  • Any Replication? No single study can provide conclusive answers to scientists’ questions. Research results need to be replicated by different investigators using the same scientific methods, but with a new set of volunteers. Once studies are replicated, we can be more confident the outcomes are valid.
  • Significant results? When research findings are “statistically significant” it means the different outcomes between experimental and control groups were probably not owed to chance. “Clinically significant” findings have to do with the size or intensity of a treatment’s observed effects.
  • For example, a diabetes drug trial may report statistically significant differences (not owed to chance) between the experimental and control groups, but the differences may be clinically insignificant, or too small to consider the new drug useful.

It’s also important to look at the date of each study. If it’s more than a few years old, newer research might have altered scientists’ view of the drug or treatment. Curious people might utilize the National Library of Medicine’s database of published studies at the website PubMed (link below).

Sources: National Center for Complementary and Integrative Health; PubMed
Photo credit: Petras Gagilas

Get Free Diabetic Supplies

For a limited time only, you can reduce diabetic supplies costs by more than 90%. Enrolling just take a few minutes. Fill out the form, speak to a representative and get diabetic supplies delivered to your door at little or no cost. Also, you will get a free Diabetes Meal Plan from a Registered Dietitian-Certified Diabetes Educator.

Enter your information below to see if you qualify.

By clicking Submit, you agree to send your info to InformationAboutDiabetes.com who may contact you with updates and information and we agree to use it according to our privacy policy.

More Articles

Chamomile tea has long been prized for its calming properties, but few people realize it’s also beneficial for glucose regulation. Traditionally,...

Matcha tea is a rich, creamy, full-bodied beverage with amazing nutritional properties that address several diabetes health concerns. The trace...

One way to ensure our body gets a variety of nutrients is eating nutrient-dense foods, and one of the most nutrient-dense foods on our planet is...

It would be interesting to know how many people with diabetes actually use blood glucose control solutions to regularly check the accuracy of...

A mood is an internal state or condition of feeling. It colors everything else we experience, much like colored sunglasses add a tint to...

More Articles

Diabetes is a health condition that disrupts the body’s normal production of insulin. Currently, more than one million Americans are diagnosed...

The HbA1c blood test, more commonly known as the A1C, is both a very useful and a very cool calculation of your average blood glucose levels over...

Chamomile tea has long been prized for its calming properties, but few people realize it’s also beneficial for glucose regulation. Traditionally,...

A mood is an internal state or condition of feeling. It colors everything else we experience, much like colored sunglasses add a tint to...

Oil pulling therapy derives from Ayurveda, a holistic healing system developed thousands of years ago in India. Ayurvedic medicine maintains that...

You may think beer, wine, and liquor would be categorized as food, but in reality, alcohol is a drug. Just like medications, alcohol has powerful...

Hot weather does not directly alter blood glucose levels. However, sweltering temperatures affect our metabolism and the release of hormones. Heat...

When it comes to certain foods, there are always questions as to whether or not a diabetic can have them without...

Those who have not yet been diagnosed with type 2 diabetes can greatly reduce their susceptibility by doing one key...

Matcha tea is a rich, creamy, full-bodied beverage with amazing nutritional properties that address several diabetes health concerns. The trace...

The different sugar content of fruits can be confusing when you are trying to manage your...

A diabetes meal plan is a guide indicating what types of foods, and how much of them, people should eat at meal and snack time. Following a meal...

The most convenient places in a fridge to store our stock of insulin may not be the best places. We tend to think our refrigerators maintain a...

This article was written exclusively for Information About Diabetes by Sarah Havemann, a 21-year-old type 1 diabetic who developed the disease...

There are many causes for both male and female hair loss, including heredity, diet and illness. Could taking prescription insulin be one more...