Meglitinides

..also known as Repaglinide, Nateglinide or Mitiglinide

Meglitinides such as Prandin and Starlix, are oral diabetes drugs used to treat Type 2 diabetes when an improved diet and exercise regime have failed to improve high blood sugar.

The meglitinides Prandin and Starlix work by stimulating your pancreas to produce more insulin in a similar way to Amaryl and the sulfonylurea medications.

These meglitinides are quick working and the effects are of short duration. They are designed to be taken immediately before each meal and attempt to mimic the normal effects of insulin after eating. They are particularly suitable for patients who do not maintain a regular meal schedule. They are also useful for patients with kidney problems.

Meglitinides are often prescribed in combination with metformin or other diabetic medications.

The side effects of Prandin or Starlix and the Meglitinides may include:

  • Diarrhea
  • Headache
  • Cardiac (slight risk only)
  • Low blood sugar (hypoglycemia)
  • Upper respiratory infections, nasal and sinus inflammation, and bronchitis
  • Joint and back pain
  • Nausea
  • Constipation

Meglitinides may interact with other drugs, both prescription and over-the-counter drugs. Please consult with your Doctor before commencing any other drug treatment.

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