- Diabetes Research
- Diabetic Testing
- Symptoms of Diabetes
- Type 1 Diabetes
- Type 2 Diabetes
- Gestational Diabetes
- Diabetes Management
- Checking blood sugar levels
- Diabetes Meal Plans
Tropical medicinal leaf may lower blood sugar levels
Leaf extracts of the tropical “water apple” plant may help lower blood sugar levels in people with diabetes, according to a study published in Food Chemistry.
Researchers from University of Malaya and Monash University in Malaysia found that the ethanolic extracts of the medicinal S. aqueum leaf are strong antihyperglycaemic agents.
They found that the leaf extracts were significantly more effective than the commercial drug acarbose in stabilizing blood sugar.
Specifically, the leaf extracts inhibited the carbohydrate hydrolysing enzymes alpha glucosidase and alpha amylase, both of which breakdown starch into sugars.
The leaf extracts also inhibited the key enzyme in the polyol pathway called aldose reductase, which is believed to cause diabetic complications in the nerves, eyes, and kidneys.
What's more, the researchers found that the leaf extracts prevent the formation of advanced glycation end products (AGEs) by 89 percent. Evidence shows that AGEs play an important role in almost all diabetes complications, according to Diabetes Journal.
The study isolated six flavonoid compounds from the ethanolic leaf extracts. Two of the flavonoids, europetin-3-O-rhamnoside and phloretin, where highly effective in inhibiting alpha glucosidase and alpha amylase.
Diabetes is the leading cause of kidney failure, new cases of blindness, and nontraumatic lower-limb amputations among adults in the United States, according to the Centers for Disease Control. The disease is a major cause of heart disease and stroke, and is the seventh leading cause of death in the US.
Grown in tropical regions
Syzygium aqueum is grown in tropical regions like Malaysia, southern India, Indonesia, the Philippines, and Thailand. The tree requires low altitudes where there is steady rainfall throughout the year.
A species of brush cherry tree, the water apple is also known as “watery rose apple” or “water guava.”
The fruit of the water apple is pear shaped, shiny and crisp, with flesh that is white, light read or red. The bark of the tree is sometimes used in herbal medicines, while the leaves are edible and sometimes used to wrap food.
Sources: Food Chemistry, Diabetes Journal, Centers for Disease Control, Purdue University
The information provided on InformationAboutDiabetes.com is designed to support, not replace, the relationship that exists between a patient/site visitor and his/her health professional. This information is solely for informational purposes and does not constitute the practice of medicine. We encourage all visitors to see a licensed physician or nutritionist if they have any concerns regarding health issues related to diet, personal image and any other topics discussed on this site. Neither the owners or employees of InformationAboutDiabetes.com nor the author(s) of site content take responsibility for any possible consequences from any treatment, procedure, exercise, dietary modification, action or application of medication which results from reading this site. Always speak with your primary health care provider before engaging in any form of self treatment. Please see our Legal Statement for further information.