Statins linked to 46-percent increased diabetes risk for men
The use of statins can increase diabetes risk by 46 percent in men, according to new research published in Diabetologia.
Even after accounting for various factors like age, body mass index, waist circumference or physical activity, the study revealed that patients treated with statins were more likely to develop diabetes, especially if they were taking higher doses of these medications.
The statins mentioned in the study were simvastatin (Zocor) and atorvastatin (Lipitor).
Insulin sensitivity and insulin secretion decreased
The study included 8,749 non-diabetic men between the ages of 45 and 73 who were tracked for a period of 5.9 years.
Overall, statin treatment was associated with a 24 percent decrease in insulin sensitivity and a 12 percent decrease in insulin secretion.
"Statin therapy was associated with a 46% increased risk of type 2 diabetes after adjustment for confounding factors, suggesting a higher risk of diabetes in the general population than previously reported," the researchers wrote.