When researchers compared the two one a day medications sitagliptin and glimepiride they found that the medication sitagliptin produces a much lower rate of hypoglycemic episodes than glimepiride. In addition to documented weight loss in type 2 diabetics. This of course for over weight and obese diabetics is a bonus with all the research being done on the connection to diabetes and obesity.
The study that is currently in process involves 1,035 type 2 diabetics. By week 30 of the study, half of the diabetics were given sitagliptin and half were given glimepiride in a combination with the medication metformin. 22% of the diabetic patients in the study that were taking the metformin and glimepiride experienced episodes of hypoglycemia while only 7% of the diabetic patients taking the metformin and sitagliptin had episodes of hypoglycemia. The diabetics taking the sitagliptin also had a weight loss percentage of about a pound. While the diabetics taking glimepiride had a weight gain of almost two pounds.
Overall sitagliptin proved to be a “better” diabetic medication with more benefits than glimepiride when combined with metformin.
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