Despite major advances in kidney care over the last two decades, type 1 diabetes patients with kidney dysfunction still have high rates of kidney failure and heart-related death, researchers have found. The findings show that more effective treatments are needed for these patients, according to the a new study.
The Study
“The new study included 423 white patients with type 1 diabetes who developed macroalbuminuria and were enrolled in the study between 1991 and 2004. Most of the patients (98 percent) were followed through 2008.
During the follow-up, 172 patients developed end-stage renal disease, and 70 of these patients died. Another 29 study participants died before developing end-stage renal disease.”
The Results
Between 1991 and 2008, more patients received treatments to protect their kidneys (treatments increased from 56 percent to 82 percent) and significant improvements were noted in patients' blood pressure and cholesterol levels.
Conclusion
"New therapies need to be developed including more aggressive or experimental protocols to stop or retard declining renal function, which leads to end-stage renal disease," Krolewski added.
The study was released online in advance of publication in an upcoming print issue of the Journal of the American Society of Nephrology.
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