John Hopkins Researchers Have Found a Potential Inroad to Diabetes Treatment
A number of factors play a part in the pancreases beta cells performing correctly when signals are received the pancreas releases the insulin. If the signal does not reach the pancreas at the appropriate time, it is similar to a short circuit. Researchers have discovered what makes the circuit malfunction.
Protein Kinase A
"Pancreatic beta cells are influenced by hormonal, metabolic and electrical Signals and something must be integrating all of these inputs to determine how to generate the cell's output," says Jin Zhang, Ph.D., an associate professor of pharmacology and molecular sciences at Johns Hopkins. "We have discovered a tunable circuit that may control the behavior of the cell." What the researchers is basically saying in the statement above is that the (protein kinase A) acts as a switch and turns on and does what it needs to do until it is done and turns off.
Further evaluation is being performed to see if there is a way to have all components work together instead of independently.