Heart Disease Likely To Manifest in Preadolescent Children with Type 1 Diabetes
Cardiovascular disease is the leading cause of death in patients with diabetes. Patients with type 1diabetes have a 200 percent to 400 percent greater chance of developing cardiovascular disease than people who do not have diabetes.
The researchers at the Medical College of Wisconsin at Children's Hospital of Wisconsin discovered the early signs of cardiovascular disease are likely to become apparent before the onset of puberty in many diabetic children. Diabetic children with a family history of heart disease or who have high blood pressure are at a higher risk of developing heart disease. Blood samples were collected from all the diabetic children in the study to monitor their cholesterol and sugar levels.
The test results revealed that, the blood vessels of children with type 1 diabetes had a lower FMD percentage change, which means their blood vessels were less flexible than the control group of children who did not have diabetes. This suggests that higher circulating glucose results in increased rigidity of blood vessels. The patients with diabetes also had vascular inflammation, which is a known cause of future cardiovascular risk.