A recent study shows that managing glucose levels by using a closed-loop insulin pump system is able to deliver the same benefits as using a system that is open-looped. Both systems are used to help those with type 1 diabetes to control their disease and to ward off the possible onset of a hypoglycemia episode.
The research was conducted at the European Association for the Study of Diabetes (EASD).
The difference in the two systems is based on how the dosage is delivered. In an open-looped system, the wearer makes the determination concerning dosage. But a closed-looped system acts as an artificial pancreas. This means that the insulin pump decides when insulin and glucagon is to be delivered.
The results of the study came from monitoring 10 patients with type 1 diabetes who were over the age of 55. Both kinds of systems were used on each patient and glucose readings were taken by way of veins and sensors.
The participants were required to partake of a specially-designed 40 gram carb breakfast which was proceeded a few hours later by half an hour of moderate exercise. They were then given a lunch consisting of 60 carbs approximately an hour and a half later. The study was conducted over a three day period.
When venous glucose concentration results from both systems were compared, there appeared to be no significant differences. However, when venous glucose values were checked on closed-loop patients, there was a substantial increase after exercising. The same increase could be seen with closed-loop patients who exercised after breakfast.
Arianne Van Bon, of the Academic Medical Center in Amsterdam summed up the findings.
“Exercise is still a challenge for the closed-loop system,” said Van Bon.
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