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Researchers at the National Institute of Diabetes and Digestive and Kidney Diseases lead by Karin G. Stenkula, Ph.D. had the following to say about the research they have been performing. “With an understanding of how these transporters in fat cells respond to insulin, we could detect the differences between an insulin-sensitive cell and an insulin-resistant cell, to learn how the response becomes impaired. We hope to identify when a person becomes pre-diabetic, before they go on to develop diabetes."
By studying lab rats, the team was able to learn how insulin gets fat cells to take in the glucose. They used healthy live rat cells to discovery how insulin effects the fat cells. Now that the researchers are better, able to understand the process they will start a human study that involves observing the fat cells of people who are insulin resistant.
By watching how the cells react in an insulin resistant person who has not developed diabetes researchers hope to be able to identify at what stage a person becomes a higher risk for developing diabetes and intervention with lifestyle changes and diet and exercise may be able to prevent the onset of diabetes.
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