Link Between High Blood Sugar, Alzheimer's Found
New research suggests that diets high in sugar raises risks of Alzheimer's, the most common form of dementia. The researchers also believe that this points towards a likelihood that sugar modulation issues, including diabetes, may be have the same risks. Biological links between high blood sugar and dementia are a new area of research.
The researchers at the University of Bath compared brain samples from 30 people with and without Alzheimer's they'd tested for protein glycation, a modification caused by high glucose levels. They found that those with Alzheimer's and glycation caused a specific enzyme to stop working.
The enzyme, already associated with Alzheimer's, is now linked to diabetes.
“We know that diabetes can double a person’s risk of developing dementia but we still don’t really understand how the two conditions are linked - this study offers a vital clue," said Dr Clare Walton, Research Manager at Alzheimer’s Society.
This research provides a likely biological mechanism for the high blood glucose and Alzheimer's link. The goal is to find a way to lessen or eliminate higher risks of dementia in diabetics. The researchers are now investigating whether this same effect is found in living patients and can be tested through blood.